Rapid and specific detection of the O15:K52:H1 clonal group of Escherichia coli by gene-specific PCR.

نویسندگان

  • James R Johnson
  • Krista Owens
  • Montse Sabate
  • Guillem Prats
چکیده

Primers specific for Escherichia coli O15:K52:H1 were devised based on a novel single-nucleotide polymorphism identified within the housekeeping gene fumC, i.e., G594A. In experiments comparing various reference typing methods, the new primers provided 100% sensitivity and specificity for the O15:K52:H1 clonal group, including 162 diverse clinical and reference E. coli isolates.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Clonal group distribution of fluoroquinolone-resistant Escherichia coli among humans and companion animals in Australia.

OBJECTIVES To determine the phylogenetic group distribution and prevalence of three major globally disseminated clonal groups [clonal group A (CGA) and O15:K52:H1, associated with phylogenetic group D, and sequence type ST131, associated with phylogenetic group B2] among fluoroquinolone-resistant extra-intestinal Escherichia coli isolates from humans and companion animals in Australia. METHOD...

متن کامل

Development of 16S rRNA targeted PCR methods for the detection of Escherichia coli in Rainbow trout (Oncorhynchus mykiss)

  Objectives: The presence of E.coli in fish intended for human consumption may constitute a potential danger, not only in causing disease, but also because of the possible transfer of antibiotic resistance from aquatic bacteria to those infecting humans. The objective of this study was to develop an improved PCR method based on species – specific 16 S rRNA gene primers (FES,...

متن کامل

Evaluation of ehxA, stx1, and stx2 Virulence Gene Prevalence in Cattle Escherichia coli Isolates by Multiplex PCR

  Today, it is nearly 25 years past from investigation of Shiga toxigenic Escherichia coli (STEC) which is able to produce Shiga toxins and cause different gastroenteritis. Since incidence of gastroenteritis due to STEC is increasing, it's necessary to develop rapid, specific and accurate procedures like PCR. In this study, we used PCR method to detect and identify STEC in cultures of 55 Escher...

متن کامل

Detection of the eaeA Gene in Escherichia coli Isolated from Broiler Chickens by Polymerase Chain Reaction

The aim of this study was to isolate Escherichia coli from chickens and to determine the presence of the eaeA gene, a virulence factor detected in Escherichia coli, in the isolates by polymerase chain reaction (PCR). Different chicken organs (lung, liver and spleen) were inoculated onto blood agar and biochemical tests were performed on the suspicious isolates. Escherichiacoliwas isolated from ...

متن کامل

تشخیص ژن اختصاصی eae باکتری انتروپاتوژنیک اشرشیاکلی با استفاده از روش نوین PCR-ELISA

Background and purpose: Enteropathogenic Escherichia coli from Enterobacteriaceae family is one of the most common causes of chronic diarrhea in children and infants. Polymerase Chain Reaction (PCR) method is commonly used for detection of enteropathogenic Escherichia coli species, but there are some disadvantages with this method due to the use of gel electrophoresis and staining with ethidium...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Journal of clinical microbiology

دوره 42 8  شماره 

صفحات  -

تاریخ انتشار 2004